What is Hepatitis?
Hepatitis refers to inflammation of the liver caused by:
- Viral infections
- Toxic substances (alcohol, certain drugs)
- Autoimmune disorders
The five main hepatitis viruses are types A, B, C, D, and E.
Global Burden of Viral Hepatitis
- 1.34 million deaths annually
- ~2 million new infections every year
- 287 million people live with chronic hepatitis B or C globally
- Most infected people remain unaware of their infection
- Chronic hepatitis B and C account for over 90% of deaths and disability
- They are major causes of cirrhosis, liver failure, and liver cancer
India's Hepatitis Burden
| Metric | Figure |
|---|---|
| Chronic Hepatitis B | 29 million |
| Chronic Hepatitis C | 5.5 million |
| Global Ranking | 2nd among top 10 countries |
| Share of global HBV carrier pool | 10-15% |
Seroprevalence in India (2021 HIV Sentinel Surveillance)
- Hepatitis B: 0.85% (~1 in 118 people)
- Hepatitis C: 0.29% (~1 in 345 people)
Diagnosis and Vaccination Gaps
- Diagnosis rate for hepatitis B: Only 2.4%
- Birth-dose vaccination coverage: ~63%
- Third-dose childhood coverage: ~93%
Types of Hepatitis: Transmission, Prevention & Treatment
Hepatitis A (HAV) and Hepatitis E (HEV)
- Transmission: Faecal-oral route through contaminated food/water; linked to poor sanitation
- Prevention: Safe drinking water, proper hygiene, sanitation; Hepatitis A vaccine available
- Treatment: Usually self-limiting; supportive care with hydration and nutrition
Hepatitis B (HBV)
- Transmission: Mother-to-child during birth; contact with infected blood, blood products, body fluids
- Prevention: Hepatitis B vaccine under Universal Immunisation Programme (birth dose within 24 hours, followed by doses at 6, 10, 14 weeks); safe injection and blood transfusion practices
- Treatment: Antiviral medicines for eligible chronic patients
Hepatitis C (HCV)
- Transmission: Unsafe injections, medical procedures, sharing needles/syringes, infected blood products
- Prevention: Safe injection and blood transfusion practices; harm-reduction measures (needle-exchange programmes)
- Treatment: Pan-genotypic Direct-Acting Antiviral (DAA) drugs; cure rate in 12-24 weeks
- No vaccine available
Hepatitis D (HDV)
- Transmission: Contact with infected blood, blood products, body fluids
- Note: Occurs only in persons already infected with Hepatitis B
- Prevention: Hepatitis B vaccination protects against HDV
- Treatment: Specialist care focusing on underlying HBV infection
WHO Elimination Targets (By 2030)
- 90% reduction in new hepatitis B infections
- 65% reduction in hepatitis-related deaths
- 90% diagnosis coverage
Government Initiatives: National Viral Hepatitis Control Programme
Launched: 2018
Objectives:
- Provide screening, diagnosis, and treatment services
- Reduce hepatitis-related illness and deaths
- Support UN Sustainable Development Goals
Key Features
| Component | Details |
|---|---|
| Coverage | Hepatitis A, B, C, D, E |
| Approach | Preventive, promotive, curative |
| Surveillance | IDSP for Hepatitis A and E monitoring |
| Treatment | Free diagnostics and medicines for B and C |
| Monitoring | NVHCP Management Information System portal |
Integration with Other Health Programmes
- RMNCHA+Nutrition Programme: Universal screening of pregnant women for hepatitis B
- Universal Immunisation Programme: Hepatitis B birth-dose for all newborns; HBIG for newborns of HBV-positive mothers within 24 hours
- National AIDS Control Programme: Screening of high-risk groups; vaccination of healthcare workers
- National TB Elimination Programme: Molecular testing machines used for hepatitis diagnosis
- Blood Transfusion Services: Link positive donors to healthcare facilities
- Helpline: Toll-free number 1800-11-6666
Early Symptoms to Watch
- Persistent fatigue
- Poor appetite
- Nausea
- Abdominal discomfort
- Dark urine
- Jaundice
Note: Most people show no symptoms during early stages, allowing disease to progress silently
Challenges Remain
- Low awareness and misinformation
- Social stigma
- Weak integration with primary healthcare
- High treatment costs
- Uneven birth-dose vaccination coverage
- Limited access at grassroots level
Constitutional/Policy Provisions
- Article 21: Right to life includes right to health
- SDG Goal 3: Good health and well-being
- Universal Immunisation Programme: Part of National Health Mission