What is Hepatitis?

Hepatitis refers to inflammation of the liver caused by:

  • Viral infections
  • Toxic substances (alcohol, certain drugs)
  • Autoimmune disorders

The five main hepatitis viruses are types A, B, C, D, and E.

Global Burden of Viral Hepatitis

  • 1.34 million deaths annually
  • ~2 million new infections every year
  • 287 million people live with chronic hepatitis B or C globally
  • Most infected people remain unaware of their infection
  • Chronic hepatitis B and C account for over 90% of deaths and disability
  • They are major causes of cirrhosis, liver failure, and liver cancer

India's Hepatitis Burden

MetricFigure
Chronic Hepatitis B29 million
Chronic Hepatitis C5.5 million
Global Ranking2nd among top 10 countries
Share of global HBV carrier pool10-15%

Seroprevalence in India (2021 HIV Sentinel Surveillance)

  • Hepatitis B: 0.85% (~1 in 118 people)
  • Hepatitis C: 0.29% (~1 in 345 people)

Diagnosis and Vaccination Gaps

  • Diagnosis rate for hepatitis B: Only 2.4%
  • Birth-dose vaccination coverage: ~63%
  • Third-dose childhood coverage: ~93%

Types of Hepatitis: Transmission, Prevention & Treatment

Hepatitis A (HAV) and Hepatitis E (HEV)

  • Transmission: Faecal-oral route through contaminated food/water; linked to poor sanitation
  • Prevention: Safe drinking water, proper hygiene, sanitation; Hepatitis A vaccine available
  • Treatment: Usually self-limiting; supportive care with hydration and nutrition

Hepatitis B (HBV)

  • Transmission: Mother-to-child during birth; contact with infected blood, blood products, body fluids
  • Prevention: Hepatitis B vaccine under Universal Immunisation Programme (birth dose within 24 hours, followed by doses at 6, 10, 14 weeks); safe injection and blood transfusion practices
  • Treatment: Antiviral medicines for eligible chronic patients

Hepatitis C (HCV)

  • Transmission: Unsafe injections, medical procedures, sharing needles/syringes, infected blood products
  • Prevention: Safe injection and blood transfusion practices; harm-reduction measures (needle-exchange programmes)
  • Treatment: Pan-genotypic Direct-Acting Antiviral (DAA) drugs; cure rate in 12-24 weeks
  • No vaccine available

Hepatitis D (HDV)

  • Transmission: Contact with infected blood, blood products, body fluids
  • Note: Occurs only in persons already infected with Hepatitis B
  • Prevention: Hepatitis B vaccination protects against HDV
  • Treatment: Specialist care focusing on underlying HBV infection

WHO Elimination Targets (By 2030)

  • 90% reduction in new hepatitis B infections
  • 65% reduction in hepatitis-related deaths
  • 90% diagnosis coverage

Government Initiatives: National Viral Hepatitis Control Programme

Launched: 2018

Objectives:

  • Provide screening, diagnosis, and treatment services
  • Reduce hepatitis-related illness and deaths
  • Support UN Sustainable Development Goals

Key Features

ComponentDetails
CoverageHepatitis A, B, C, D, E
ApproachPreventive, promotive, curative
SurveillanceIDSP for Hepatitis A and E monitoring
TreatmentFree diagnostics and medicines for B and C
MonitoringNVHCP Management Information System portal

Integration with Other Health Programmes

  • RMNCHA+Nutrition Programme: Universal screening of pregnant women for hepatitis B
  • Universal Immunisation Programme: Hepatitis B birth-dose for all newborns; HBIG for newborns of HBV-positive mothers within 24 hours
  • National AIDS Control Programme: Screening of high-risk groups; vaccination of healthcare workers
  • National TB Elimination Programme: Molecular testing machines used for hepatitis diagnosis
  • Blood Transfusion Services: Link positive donors to healthcare facilities
  • Helpline: Toll-free number 1800-11-6666

Early Symptoms to Watch

  • Persistent fatigue
  • Poor appetite
  • Nausea
  • Abdominal discomfort
  • Dark urine
  • Jaundice

Note: Most people show no symptoms during early stages, allowing disease to progress silently

Challenges Remain

  • Low awareness and misinformation
  • Social stigma
  • Weak integration with primary healthcare
  • High treatment costs
  • Uneven birth-dose vaccination coverage
  • Limited access at grassroots level

Constitutional/Policy Provisions

  • Article 21: Right to life includes right to health
  • SDG Goal 3: Good health and well-being
  • Universal Immunisation Programme: Part of National Health Mission